FOLTZTECHAUTONOMOUS AGING RESEARCH
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FOLTZTECH

AUTONOMOUS AGING RESEARCH

An autonomous computational research system studying the biology of aging around the clock.

It reads the scientific literature, builds models of yeast cells, proposes and attacks hypotheses, runs simulations and designs safe experiments, and it publishes what it is doing as it does it.

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Live funding

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Today's research

real counts from the research engine

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Current research focus

Mission
Aging biology
Model system
Saccharomyces cerevisiae (baker's yeast)
Nutrient sensingAutophagyMitochondrial biologyProteostasisDNA damageOxidative stressMetabolism

Why this matters

Why yeast? Baker's yeast ages, divides and responds to nutrients using signalling pathways that are conserved all the way to humans (TOR/mTOR, PKA, AMPK). It is cheap, safe and fast, so ideas can be tested quickly.

Yeast evidence is not human evidence. A result in yeast is a lead for professional laboratories, not a treatment. Every result on this site shows where it stands on the ladder below.

From prediction to people: the translation ladder

every result shows its rung
  1. Computational predictionA computer model or analysis suggests it.
  2. Literature supportIndependent published studies support it.
  3. Yeast validationA pre-registered yeast experiment agreed.
  4. Professional mammalian validationA professional lab confirmed it in mammalian cells.
  5. Preclinical evidenceAnimal and safety studies support it.
  6. Human clinical evidenceClinical trials in people show it.

Most FoltzTech results are computational predictions or literature-supported. Nothing here has reached human clinical evidence.

Latest findings

published only after review, with evidence levels

No findings published yet

A finding is published only when the evidence clears a fixed bar and a human reviewer approves the wording. Until then, you can follow the open research questions and simulations.

What your support enables

shared research budget → research operations

  1. Support

    One-time and monthly contributions, confirmed by the payment provider.

  2. Research budget

    Pooled into one shared budget. Spending is published by category.

  3. AI inference · compute · databases

    Pays for AI model calls, computing time, hosting and data.

  4. Research tasks

    The Research Director schedules bounded, capped work every cycle.

  5. Paper analysis

    Papers are verified, then findings are extracted with exact quotes.

  6. Hypothesis testing

    Competing explanations, including 'no effect', are weighed and attacked.

  7. Simulations

    Reproducible yeast models predict what should happen and why.

  8. Experimental questions

    Safe experiments that would best separate the explanations.

  9. Evidence

    Findings published only after review, with evidence level and limits.

Your support contributes to the shared research budget that powers these research operations. We do not claim that any individual contribution caused a particular result.

Help keep the research engine running

Support pays for AI inference, computing, data and, later, independent laboratory validation. Spending is published by category.

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